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In a stem cell transplant, the patient gets high-dose chemotherapy to kill the cells in the bone marrow. Then the patient receives new, healthy blood-forming stem cells. When stem cell transplants were first developed, the new stem cells came from bone marrow, and so this was known as a bone marrow transplant.What is tandem autologous transplant treatment?
Tandem autologous transplant treatment. An autologous stem cell transplant involves collecting a patient's own healthy bone marrow stem cells prior to giving high-dose chemotherapy and then giving them back after the treatment. This way, the healthy stem cells are not damaged by the high-dose chemotherapy.How are stem cells collected for a bone marrow transplant?
Once a match for a patient needing a bone marrow transplant is found, then stem cells will be collected either by a bone marrow harvest. This is a collection of stem cells with a needle placed into the soft center of the bone marrow. Or by a peripheral blood stem cell collection.Are tandem transplants better than single transplants for cancer?
Tandem transplants have become the standard of care for certain cancers. High-risk types of the childhood cancer neuroblastoma and adult multiple myeloma are cancers where tandem transplants seem to show good results. But doctors don’t always agree that these are really better than a single transplant for certain cancers.