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Table 1, Statin Dosing and ACC/AHA Classification of Intensity - Statin
https://www.ncbi.nlm.nih.gov/books/NBK583664/table/ch1.tab1/
WEBStatin Low-Intensity Dosage (LDL-C Reduction <30%) Moderate-Intensity Dosage (LDL-C Reduction 30% to <50%) High-Intensity Dosage (LDL-C Reduction ≥50%) Atorvastatin: NA: 10 to 20 mg: 40 to 80 mg: Fluvastatin: 20 to 40 mg: 40 mg 2x/day; XL 80 mg: NA: Lovastatin: 20 mg: 40 to 80 mg: NA: Pitavastatin: NA: 1 to 4 mg: NA: Pravastatin: 10 to …
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Cholesterol Management: ACC/AHA Updates Guideline | AAFP
https://www.aafp.org/pubs/afp/issues/2019/0501/p589.html
WEBMay 1, 2019 · Based on high-quality evidence from RCTs, moderate-intensity statin therapy should be initiated without calculating a 10-year ASCVD risk for all patients 40 to 75 years of age with diabetes...
DA: 86 PA: 95 MOZ Rank: 88
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Understanding statin intensity - Harvard Health
https://www.health.harvard.edu/heart-health/understanding-statin-intensity
WEBJul 1, 2023 · Statin dosages fall into three categories (low, moderate, or high) based on how much the medication can lower LDL. The choice of a statin depends on a person's risk.
DA: 96 PA: 40 MOZ Rank: 53
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2019 ACC/AHA Guideline on the Primary Prevention of …
https://www.ahajournals.org/doi/10.1161/CIR.0000000000000678
WEBTherefore, moderate-intensity statin therapy is indicated for primary prevention in patients 40 to 75 years of age with diabetes. Patients with primary severe hypercholesterolemia (LDL-C ≥190 mg/dL [≥4.9 mmol/L]) have a high risk of ASCVD S4.3-23 and premature and recurrent coronary events.
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2019 ACC/AHA Guideline on the Primary Prevention of …
https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2019/03/07/16/00/2019-acc-aha-guideline-on-primary-prevention-gl-prevention
WEBMar 17, 2019 · If CACs 1-100, it is reasonable to initiate moderate-intensity statin for persons ≥55 years. If CAC >100 or 75th percentile or higher, use statin at any age. Risk ≥20% (high risk). Risk discussion to initiate high-intensity statin to reduce LDL-C by ≥50%.
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CHOLESTEROL CLINICAL PRACTICE GUIDELINES
https://www.ahajournals.org/doi/pdf/10.1161/CIR.0000000000000624
WEBstatin therapy; and patient preferences and values in shared decision-making. 7. In adults 40 to 75 years of age without dia-betes mellitus and with LDL-C levels ≥70 mg/ dL (≥1.8 mmol/L), at a 10-year ASCVD risk of ≥7.5%, start a moderate-intensity statin if a discussion of treatment options favors statin therapy.
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Key Recommendations on Managing Dyslipidemia for …
https://www.aafp.org/pubs/afp/issues/2021/0415/p455.html
WEBApr 15, 2021 · Strong evidence supports moderate-dose statins as the best therapy in primary prevention for patients at elevated risk, with relative risk reductions in cardiovascular events and mortality of...
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Low-density lipoprotein cholesterol-lowering therapy in the …
https://www.uptodate.com/contents/low-density-lipoprotein-cholesterol-lowering-therapy-in-the-primary-prevention-of-cardiovascular-disease
WEBNov 2, 2023 · Based on their estimated 10-year CVD risk, the patient and their provider (s) can decide whether a 30 percent relative risk reduction, which is a reasonable expectation for statin therapy, translates into an absolute risk reduction large enough to be worth the cost, burdens, and potential side effects of daily therapy [ 1 ].
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2019 ACC/AHA Guideline on the Primary Prevention of …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351755/
WEBSep 10, 2019 · In adults at intermediate risk (≥7.5% to <20% 10-year ASCVD risk), statin therapy reduces risk of ASCVD, and in the context of a risk discussion, if a decision is made for statin therapy, a moderate-intensity statin should be recommended (S4.3–2–S4.3–9).
DA: 5 PA: 27 MOZ Rank: 57
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Statin Use for Primary Prevention of CVD: USPSTF …
https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2022/08/23/22/22/statin-use-for-the-primary-prevention
WEBAug 24, 2022 · Convincing evidence that statin use reduces the probability of CVD events (MI or ischemic stroke) and all-cause mortality by at least a moderate amount in adults aged 40-75 years with no history of CVD and who have ≥1 CVD risk factors (i.e., dyslipidemia, diabetes, hypertension, or smoking) and an estimated 10-year CVD event …
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