| Keyword | CPC | PCC | Volume | Score | Length of keyword |
|---|---|---|---|---|---|
| a level biology dna replication | 1.27 | 0.3 | 7133 | 15 | 31 |
| a | 1.62 | 0.7 | 2018 | 1 | 1 |
| level | 0.78 | 0.6 | 3395 | 20 | 5 |
| biology | 0.71 | 0.3 | 1300 | 45 | 7 |
| dna | 1.58 | 0.4 | 7945 | 46 | 3 |
| replication | 1.18 | 0.9 | 3275 | 8 | 11 |
Major steps involved in DNA replication are as follows: Each strand in a parental duplex DNA acts as a template for synthesis of a daughter strand and remains basepaired to the new strand, forming a daughter duplex (semiconservative mechanism). New strands are formed in the 5′ to 3′ direction. Replication begins at a sequence called an origin.
How does DNA replicate itself?Because DNA is a base-paired double helix, it replicates itself by unwinding and using each of its strands as a template to form a new strand. Hydrogen bonds are broken during unwinding. There is breakage of hydrogen bonds between complementary base pairs on the two polynucleotide chains. An enzyme called DNA helicase is involved.
What is the role of the double helix in DNA replication?Each strand in the double helix acts as a template for synthesis of a new, complementary strand. New DNA is made by enzymes called DNA polymerases, which require a template and a primer (starter) and synthesize DNA in the 5' to 3' direction. During DNA replication, one new strand (the leading strand) is made as a continuous piece.
What enzymes are involved in DNA replication?During DNA replication, one new strand (the leading strand) is made as a continuous piece. The other (the lagging strand) is made in small pieces. DNA replication requires other enzymes in addition to DNA polymerase, including DNA primase, DNA helicase, DNA ligase, and topoisomerase.
