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TAFINLAR® (dabrafenib) + MEKINIST® (trametinib) | Official Site …
https://www.us.tafinlarmekinist.com/
WEBTAFINLAR and MEKINIST are prescription medicines that can be used in combination to treat a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to other parts of the body (metastatic NSCLC), and that has a …
DA: 17 PA: 13 MOZ Rank: 27
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TAFINLAR® (dabrafenib) + MEKINIST® (trametinib) Treatment
https://www.us.tafinlarmekinist.com/advanced-melanoma/about-tafinlar-mekinist/treatment-with-tafinlar-mekinist/
WEBTAFINLAR + MEKINIST is a combination therapy for BRAF -positive (also seen as BRAF +) melanoma. TAFINLAR + MEKINIST is a targeted therapy that can be used for 2 different types of melanoma treatment: Adjuvant (after surgical removal) treatment of BRAF + melanoma, to help prevent your melanoma from coming back after surgery.
DA: 74 PA: 75 MOZ Rank: 80
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TAFINLAR® (dabrafenib) + MEKINIST® (trametinib) | HCP
https://www.hcp.novartis.com/products/tafinlar-mekinist/
WEBINDICATIONS. TAFINLAR, in combination with MEKINIST, is indicated for: the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations as detected by an FDA-approved test.
DA: 85 PA: 93 MOZ Rank: 58
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FDA approves dabrafenib–trametinib for BRAF-positive cancers
https://www.cancer.gov/news-events/cancer-currents-blog/2022/fda-dabrafenib-trametinib-braf-solid-tumors
WEBJul 21, 2022 · The Food and Drug Administration (FDA) recently approved the combination of the targeted drugs dabrafenib (Tafinlar) and trametinib (Mekinist) for the treatment of people with nearly any type of advanced solid tumor that has a specific mutation in a …
DA: 6 PA: 18 MOZ Rank: 93
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FDA approves new uses for two drugs administered together for …
https://www.fda.gov/news-events/press-announcements/fda-approves-new-uses-two-drugs-administered-together-treatment-braf-positive-anaplastic-thyroid
WEBBoth Tafinlar and Mekinist are also approved for use, alone or in combination, to treat BRAF V600 mutation-positive metastatic melanoma. Additionally, Tafinlar and Mekinist are approved for...
DA: 74 PA: 50 MOZ Rank: 32
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Novartis Tafinlar + Mekinist receives FDA approval for first tumor
https://www.novartis.com/news/media-releases/novartis-tafinlar-mekinist-receives-fda-approval-first-tumor-agnostic-indication-braf-v600e-solid-tumors
WEBJun 23, 2022. Tafinlar + Mekinist, the worldwide targeted therapy leader in BRAF/MEK-inhibition, is the first and only therapy to be approved with a tumor-agnostic indication for adult and pediatric patients with solid tumors that have a BRAF V600E mutation1,2. Approval supported by results from Phase II ROAR and NCI-MATCH studies …
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Two new GSK oral oncology treatments, BRAF-inhibitor Tafinlar
https://www.gsk.com/en-gb/media/press-releases/two-new-gsk-oral-oncology-treatments-braf-inhibitor-tafinlar-dabrafenib-capsules-and-the-first-mek-inhibitor-mekinist-trametinib-tablets-approved-by-fda-as-single-agent-therapies/
WEBTafinlar and Mekinist are each approved for patients with the BRAF V600E mutation, which accounts for approximately 85 percent of all BRAF V600 mutations in metastatic melanoma. [ii] Mekinist is also approved for patients with the V600K mutation, which makes up approximately 10 percent of all BRAF V600 mutations in metastatic melanoma. 2.
DA: 12 PA: 81 MOZ Rank: 64
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TAFINLAR® (dabrafenib) + MEKINIST® (trametinib) Dosing for …
https://www.hcp.novartis.com/products/tafinlar-mekinist/metastatic-nsclc/dosing-and-administration/
WEBTAFINLAR, in combination with MEKINIST, is indicated for the treatment of patients with metastatic non-small cell lung cancer (NSCLC) with BRAF V600E mutation as detected by an FDA-approved test. Limitation of Use: TAFINLAR is not indicated for the treatment of patients with wild-type BRAF NSCLC.
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FDA D.I.S.C.O. Burst: Tafinlar in combination with Mekinist
https://www.fda.gov/drugs/resources-information-approved-drugs/fda-disco-burst-edition-fda-approval-tafinlar-dabrafenib-combination-mekinist-trametinib
WEBJul 25, 2022 · On June 22, 2022, the FDA granted accelerated approval to dabrafenib (brand name Tafinlar) in combination with trametinib (brand name Mekinist) for treatment of adult and pediatric patients 6...
DA: 64 PA: 29 MOZ Rank: 9
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FDA grants accelerated approval to dabrafenib in combination …
https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-accelerated-approval-dabrafenib-combination-trametinib-unresectable-or-metastatic-solid
WEBOn June 22, 2022, the Food and Drug Administration granted accelerated approval to dabrafenib (Tafinlar, Novartis) in combination with trametinib (Mekinist, Novartis) for the treatment of...
DA: 99 PA: 55 MOZ Rank: 38