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Alpha-synuclein - Wikipedia
https://en.wikipedia.org/wiki/Alpha-synuclein
WEBAlpha-synuclein (aSyn) is a protein that, in humans, is encoded by the SNCA gene. Alpha-synuclein is a neuronal protein that regulates synaptic vesicle trafficking and subsequent neurotransmitter release. It is abundant in the brain, while smaller amounts are found in the heart, muscle and other tissues.
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The Genetic Link to Parkinson's Disease | Johns Hopkins Medicine
https://www.hopkinsmedicine.org/health/conditions-and-diseases/parkinsons-disease/the-genetic-link-to-parkinsons-disease
WEBSNCA: SNCA makes the protein alpha-synuclein. In brain cells of individuals with Parkinson’s disease, this protein gathers in clumps called Lewy bodies. Mutations in the SNCA gene occur in early-onset Parkinson’s disease. PARK2: The PARK2 gene makes the protein parkin, which normally helps cells break down and recycle proteins.
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Society of North Carolina Archivists - SNCA Annual Meeting 2024 …
https://www.ncarchivists.org/event-5612787
WEB4 days ago · SNCA Annual Meeting 2024 - 40th Anniversary. 40th Anniversary. “Looking Back, Looking Forward” State Archives of North Carolina - 109 E Jones St. Downtown Raleigh - April 17-19, 2024. Registration Dates: In-person attendance - through Friday, April 5 - In-person registration is closed. Virtual attendance - through Friday, April 12.
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A systematic review of associations between common SNCA
https://www.nature.com/articles/s41531-021-00196-5
WEBJul 1, 2021 · Genetic variants in SNCA are an established risk factor for PD and are candidates to modify disease presentation and progression. This systematic review aimed to summarize all available primary...
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The Parkinson Disease gene SNCA: Evolutionary and structural …
https://www.nature.com/articles/srep24475
WEBApr 15, 2016 · SNCA is considered as the major causative gene involved in the early onset of familial Parkinson’s disease (FPD) characterized by five missense mutations identified so far i.e. A30P 3, E46K...
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Genetic Analysis and Literature Review of SNCA Variants in …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397385/
WEBAug 12, 2021 · Abstract. Parkinson's disease (PD) is the fastest-growing neurodegenerative disorder. Aging, environmental factors, and genetics are considered as risk factors. The alpha-synuclein gene ( SNCA ), the first pathogenic gene identified in a familial form of PD, was indisputably involved as a heritable component for familial and …
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Resequencing the complete SNCA locus in Indian patients with
https://www.nature.com/articles/s41531-024-00676-4
WEB6 days ago · The first pathogenic mutation in the SNCA gene (p.Ala53Thr) was reported in 1997 in an Italian kindred and three unrelated families of Greek origin 6. Later, mutations derived from a common ...
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Intronic enhancers of the human SNCA gene predominantly
https://www.science.org/doi/10.1126/sciadv.abq6324
WEB23 Nov 2022. Vol 8, Issue 47. DOI: 10.1126/sciadv.abq6324. Abstract. Evidence from patients with Parkinson’s disease (PD) and our previously reported α-synuclein (SNCA) transgenic rat model support the idea that increased SNCA protein is a substantial risk factor of PD pathogenesis.
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SNCA - Luxembourg
https://snca.public.lu/en.html
WEBDec 20, 2022 · Official website of the National Society of Automotive Traffic (Société nationale de circulation automobile - SNCA), responsible for procedures relating to driving licences, registration numbers, registration of new and second-hand vehicles, changes to the registration certificate.
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Sabine-Neches Chiefs' Association – 24 hour activation: 409-838 …
https://www.snchiefs.com/
WEBFeb 1, 2021 · Nederland, Texas 77627. email: [email protected]. Web Site: www.snchiefs.com. 24-Hour Activation Phone: 409-838-6371. Vision. The Sabine-Neches Chiefs’ Association (SNCA) strives to be the premier mutual aid organization serving the South East Texas community by innovative achievement of the highest level …
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