Keyword Analysis & Research: pten
Keyword Research: People who searched pten also searched
Search Results related to pten on Search Engine
-
PTEN (gene) - Wikipedia
https://en.wikipedia.org:443/wiki/PTEN_(gene)
WEBPhosphatase and tensin homolog (PTEN) is a phosphatase in humans and is encoded by the PTEN gene. Mutations of this gene are a step in the development of many cancers , specifically glioblastoma, lung cancer, breast cancer, and prostate cancer.
DA: 8 PA: 5 MOZ Rank: 97
-
PTEN gene: MedlinePlus Genetics
https://medlineplus.gov:443/genetics/gene/pten/
WEBThe PTEN gene provides instructions for making an enzyme that is found in almost all tissues in the body. The enzyme acts as a tumor suppressor, which means that it helps regulate cell division by keeping cells from growing and dividing (proliferating) too rapidly or in an uncontrolled way.
DA: 43 PA: 40 MOZ Rank: 90
-
PTEN Gene - GeneCards | PTEN Protein | PTEN Antibody
https://www.genecards.org:443/cgi-bin/carddisp.pl?gene=PTEN
WEBApr 3, 2024 · PTEN (Phosphatase And Tensin Homolog) is a Protein Coding gene. Diseases associated with PTEN include Cowden Syndrome 1 and Macrocephaly/Autism Syndrome. Among its related pathways are Prolactin Signaling and PIP3 activates AKT signaling. Gene Ontology (GO) annotations related to this gene include protein kinase …
DA: 56 PA: 59 MOZ Rank: 75
-
PTEN function, the long and the short of it - PMC - National …
https://www.ncbi.nlm.nih.gov:443/pmc/articles/PMC4043120/
WEBPhosphatase and tensin homolog deleted on chromosome ten (PTEN) is a phosphatase that is frequently altered in cancer. PTEN has phosphatase-dependent and - independent roles; and genetic alterations in PTEN lead to deregulation of protein synthesis, cell cycle, migration, growth, DNA repair, and survival signaling.
DA: 94 PA: 49 MOZ Rank: 83
-
The functions and regulation of the PTEN tumour suppressor
https://www.nature.com:443/articles/s41580-018-0015-0
WEBJun 1, 2018 · The tumour suppressor PTEN regulates various cellular processes, including maintenance of genomic stability, cell survival, migration, proliferation and metabolism.
DA: 3 PA: 71 MOZ Rank: 29
-
PTEN: Tumor Suppressor and Metabolic Regulator - PMC
https://www.ncbi.nlm.nih.gov:443/pmc/articles/PMC6046409/
WEBJul 9, 2018 · Abstract. Phosphatase and Tensin Homolog deleted on Chromosome 10 (PTEN) is a dual phosphatase with both protein and lipid phosphatase activities. PTEN was first discovered as a tumor suppressor with growth and survival regulatory functions. In recent years, the function of PTEN as a metabolic regulator has attracted significant …
DA: 69 PA: 48 MOZ Rank: 59
-
The functions of tumor suppressor PTEN in innate and adaptive …
https://www.nature.com:443/articles/cmi201730
WEBJun 26, 2017 · The tumor suppressor phosphatase and tensin homolog (PTEN) is a lipid and protein phosphatase that is able to antagonize the PI3K/AKT pathway and inhibit tumor growth. PTEN also possesses...
DA: 40 PA: 49 MOZ Rank: 47
-
PTEN Genetic Test: MedlinePlus Medical Test
https://medlineplus.gov:443/lab-tests/pten-genetic-test/
WEBWhat is it used for? The PTEN genetic test is used to look for changes in your PTEN gene. It's not a routine test. It may be used to: Find out if a change in your PTEN gene is involved in cancer. Check for inherited changes in your PTEN gene if you have:
DA: 4 PA: 19 MOZ Rank: 94
-
The functions and regulation of the PTEN tumour suppressor
https://www.nature.com:443/articles/nrm3330
WEBApr 4, 2012 · Key Points. PTEN (phosphatase and tensin homologue) is frequently disrupted in multiple sporadic tumours, and targeted by germline mutations in patients with cancer predisposition syndromes.
DA: 83 PA: 40 MOZ Rank: 48
-
The Role of PTEN in Neurodevelopment - PMC - National Center …
https://www.ncbi.nlm.nih.gov:443/pmc/articles/PMC7206585/
WEBJan 21, 2020 · Abstract. PTEN is a lipid and protein phosphatase that regulates cell growth and survival. Mutations to PTEN are highly penetrant for autism spectrum disorder (ASD). Here, we briefly review the evidence linking PTEN mutations to ASD and the mouse models that have been used to study the role of PTEN in neurodevelopment.
DA: 78 PA: 85 MOZ Rank: 45