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Role of histone N-terminal tails and their acetylation in ...
Histone N-terminal tails are central to the processes that modulate nucleosome structure and function. We have studied the contribution of core histone tails to the structure of a single nucleosome and to a …
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The N-terminal tails of histones H2A and H2B adopt two ...
The N-terminal tails of histones H2A and H2B adopt two distinct conformations in the nucleosome with contact and reduced contact to DNA
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Terminal amine isotopic labeling of substrates - Wikipedia
Terminal amine isotopic labeling of substrates (TAILS) is a method in quantitative proteomics that identifies the protein content of samples based on N-terminal fragments of each protein (N-terminal peptides) and detects differences in protein abundance among samples. Like other methods based on N-terminal peptides, this assay uses trypsinto break proteins into fragments and separates the N-terminal peptides (the fragments containing the N-termini of the original proteins) f…
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N terminal tail | definition of N terminal tail by Medical ...
a·mi·no-ter·mi·nal. ( ă-mē'nō-ter'min-ăl ), The α-NH2 group or the aminoacyl residue containing it at one end of a peptide or protein (usually on the left as written).
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How is tails used to identify N-terminal peptides?
TAILS isolates the N-terminal peptides by identifying and removing the internal tryptic peptides. This negative selection allows the TAILS method to detect all N-termini in the given samples.
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How does terminal amine isotopic labeling of substrates ( TAILS ) work?
Terminal amine isotopic labeling of substrates ( TAILS) is a method in quantitative proteomics that identifies the protein content of samples based on N-terminal fragments of each protein (N-terminal peptides) and detects differences in protein abundance among samples.
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How does tail work in the command line?
Pass the filename on the command line and use the -f (follow) option. As each new log entry is added to the log file, tail updates its display in the terminal window. You can refine the output to include only lines of particular relevance or interest.
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How is the TAILS method used in protein annotation?
The TAILS method has a number of applications including the identification of new substrates and proteases (including those that have an unknown and broad specificity) and as a way to define the termini of proteins that enables protein annotation.
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