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Understanding statin intensity - Harvard Health
https://www.health.harvard.edu/heart-health/understanding-statin-intensity
WebJul 1, 2023 · Statin dosages fall into three categories (low, moderate, or high) based on how much the medication can lower LDL. The choice of a statin depends on a person's risk.
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Cholesterol Management: ACC/AHA Updates Guideline | AAFP
https://www.aafp.org/pubs/afp/issues/2019/0501/p589.html
WebMay 1, 2019 · Based on high-quality evidence from RCTs, moderate-intensity statin therapy should be initiated without calculating a 10-year ASCVD risk for all patients 40 to 75 years of age with diabetes...
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CHOLESTEROL CLINICAL PRACTICE GUIDELINES
https://www.ahajournals.org/doi/pdf/10.1161/CIR.0000000000000624
Webstatin therapy; and patient preferences and values in shared decision-making. 7. In adults 40 to 75 years of age without dia-betes mellitus and with LDL-C levels ≥70 mg/ dL (≥1.8 mmol/L), at a 10-year ASCVD risk of ≥7.5%, start a moderate-intensity statin if a discussion of treatment options favors statin therapy.
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2019 ACC/AHA Guideline on the Primary Prevention of …
https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2019/03/07/16/00/2019-acc-aha-guideline-on-primary-prevention-gl-prevention
WebMar 17, 2019 · If CACs 1-100, it is reasonable to initiate moderate-intensity statin for persons ≥55 years. If CAC >100 or 75th percentile or higher, use statin at any age. Risk ≥20% (high risk). Risk discussion to initiate high-intensity statin to reduce LDL-C by ≥50%.
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ACC/AHA Release Updated Guideline on the Treatment of Blood Cholesterol
https://www.aafp.org/pubs/afp/issues/2014/0815/p260.html
WebAug 15, 2014 · The guideline identifies high- and moderate-intensity statin therapy for use in primary and secondary prevention ( Table 1). Less evidence is available to support nonstatin therapy for ASCVD...
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2018 Guideline on the Management of Blood Cholesterol
https://www.acc.org/~/media/Non-Clinical/Files-PDFs-Excel-MS-Word-etc/Guidelines/2018/Guidelines-Made-Simple-Tool-2018-Cholesterol.pdf
WebIf statins are indicated, reduce LDL-C levels by ≥30%, and if 10-year risk is ≥20%, reduce LDL-C levels by ≥50%. 7 In adults 40 to 75 years of age without diabetes mellitus and with LDL-C levels ≥70 mg/dL (≥1.8 mmol/L), at a 10-year ASCVD risk of ≥7.5%, start a moderate-intensity statin if a
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Statin Use for Primary Prevention of CVD: USPSTF …
https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2022/08/23/22/22/statin-use-for-the-primary-prevention
WebAug 24, 2022 · Benefits of statin use based upon moderate-intensity statins: Convincing evidence that statin use reduces the probability of CVD events (MI or ischemic stroke) and all-cause mortality by at least a moderate amount in adults aged 40-75 years with no history of CVD and who have ≥1 CVD risk factors (i.e., dyslipidemia, diabetes, hypertension, or ...
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Key Recommendations on Managing Dyslipidemia for …
https://www.aafp.org/pubs/afp/issues/2021/0415/p455.html
WebApr 15, 2021 · Strong evidence supports moderate-dose statins as the best therapy in primary prevention for patients at elevated risk, with relative risk reductions in cardiovascular events and mortality of...
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ACC/AHA lipid guidelines: Personalized care to prevent …
https://www.ccjm.org/content/87/4/231
WebApr 1, 2020 · In secondary prevention, the guidelines group patients according to their risk (high risk vs very high risk) and incorporate new nonstatin therapies as add-on, evidence-based treatment options when low-density lipoprotein (LDL-C) …
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Comparing Statins: Intensity, Dosages, and More - GoodRx
https://www.goodrx.com/classes/statins/intensity-comparison-chart
WebFeb 17, 2023 · Dosage and intensity: Typical lovastatin starting doses (10 mg to 20 mg) are considered to be low intensity. These doses will typically lower LDL by less than 30%. Higher doses (40 mg to 80 mg) are considered moderate intensity. They can lower LDL between 30% and 49%. Ways to save: Lovastatin tablets are available as a lower-cost …
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