Keyword Analysis & Research: lonidamine hk2

Keyword Analysis

Keyword	CPC	PCC	Volume	Score	Length of keyword
lonidamine hk2	0.55	0.3	5315	85	14
lonidamine	1.86	0.2	6165	42	10
hk2	1.98	0.6	6092	49	3

Keyword	CPC	PCC	Volume	Score
lonidamine hk2	1.19	0.7	5157	98

Microglial hexokinase 2 deficiency increases ATP …
nature.com

https://www.nature.com/articles/s42255-022-00643-4

WEBOct 6, 2022 · Lonidamine is a general inhibitor of all HKs 29 and has been evaluated in Phase III clinical trials for glioma 30,31. 3-BP is a specific HK2 inhibitor, with reported …

DA: 85 PA: 93 MOZ Rank: 43

Hexokinase 2 couples glycolysis with the profibrotic …
science.org

https://www.science.org/doi/10.1126/scisignal.aax4067

WEBIn that Lonidamine inhibits HK1 and HK2, yet abundance of HK1 was not increased by TGF-β or in IPF fibroblasts (Fig. 1, A, E, and F), the development of a selective HK2 … Author: Xueqian Yin, Malay Choudhury, Jeong Han Kang, Kyle J. Schaefbauer, Mi Yeon Jung, Mahefatiana Andrian... Publish Year: 2019

Author: Xueqian Yin, Malay Choudhury, Jeong Han Kang, Kyle J. Schaefbauer, Mi Yeon Jung, Mahefatiana Andrian...
Publish Year: 2019

DA: 65 PA: 5 MOZ Rank: 76

Aerobic glycolysis promotes tumor immune evasion by hexokinase2
sciencedirect.com

https://www.sciencedirect.com/science/article/pii/S155041312200345X

DA: 68 PA: 36 MOZ Rank: 40

Lonidamine potentiates the oncolytic efficiency of M1 virus …
biomedcentral.com

https://cancerci.biomedcentral.com/articles/10.1186/s12935-020-01598-w

WEBNov 2, 2020 · Lonidamine enhances M1 virus infection by inhibiting the antiviral immune response independent of HK2. Lonidamine is an HK2 inhibitor , and we confirmed that …

DA: 84 PA: 94 MOZ Rank: 83

Lonidamine potentiates the oncolytic efficiency of M1 …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607643/

WEBNov 2, 2020 · Lonidamine enhances M1 virus infection by inhibiting the antiviral immune response independent of HK2. Lonidamine is an HK2 inhibitor , and we … Author: Jing Cai, Wenbo Zhu, Yuan Lin, Jun Hu, Xincheng Liu, Wencang Xu, Ying Liu, Cheng Hu, Songmin He, Sho... DOI: 10.1186/s12935-020-01598-w Publish Year: 2020 Publication: Cancer Cell Int. 2020; 20: 532.

Author: Jing Cai, Wenbo Zhu, Yuan Lin, Jun Hu, Xincheng Liu, Wencang Xu, Ying Liu, Cheng Hu, Songmin He, Sho...
DOI: 10.1186/s12935-020-01598-w
Publish Year: 2020
Publication: Cancer Cell Int. 2020; 20: 532.

DA: 83 PA: 19 MOZ Rank: 73

Directly targeting ASC by lonidamine alleviates …
biomedcentral.com

https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-022-02682-w

WEBDec 28, 2022 · Lonidamine (LND) is a derivate of indazole-3-carboxylic acid that can inhibit the rate-limiting glycolytic enzyme hexokinase 2 (HK2) . LND is firstly …

DA: 62 PA: 99 MOZ Rank: 91

Aerobic glycolysis promotes tumor immune evasion by …
sciencedirect.com

https://www.sciencedirect.com/science/article/pii/S155041312200345X

WEBSep 6, 2022 · IHC staining of tumor tissue showed that lonidamine treatment reduced HK2-mediated IκBα T291 phosphorylation and PD-L1 expression accompanied by …

DA: 7 PA: 59 MOZ Rank: 11

Hexokinase 2 in Cancer: A Prima Donna Playing Multiple …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125560/

WEBApr 29, 2021 · Hexokinase 2 (HK2) is the most active isozyme of the family, mainly expressed in insulin-sensitive tissues. HK2 induction in most neoplastic cells contributes to their metabolic rewiring towards aerobic glycolysis, and its genetic ablation inhibits malignant growth in mouse models.

DA: 42 PA: 24 MOZ Rank: 89

Lonidamine potentiates the oncolytic efficiency of M1 …
nih.gov

https://pubmed.ncbi.nlm.nih.gov/33292203/

WEBNov 2, 2020 · In contrast, lonidamine, a reported hexokinase 2 (HK2) inhibitor, enhanced the infection and oncolytic effect of M1 virus independent of HK2.

DA: 67 PA: 96 MOZ Rank: 32