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Insulin Glargine Dosage Guide + Max Dose, Adjustments
https://www.drugs.com/dosage/insulin-glargine.html
Feb 18, 2022 · Insulin glargine 300 units/mL (U-300):-Initial dose: Approximately one-third to one-half total daily insulin requirement subcutaneously once a day; maximum glucose lowering effect may take 5 days to fully manifest and the first dose may be insufficient to cover metabolic needs during the first 24 hour; monitor closely
DA: 58 PA: 19 MOZ Rank: 58
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Twice-daily insulin glargine for patients with uncontrolled …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299157/
Dec 11, 2018 · Mean daily insulin glargine dose increased from 53 ± 20.9 units to 77.8 ± 29.4 units while on once and twice daily glargine therapy respectively, P < 0.001. Conversion from once to twice daily dosing resulted in a significant increase in the mean total daily insulin dose from 91.7 ± 45.5 to 138.3 ± 69.9 units, P < 0.01. Author: Mohsen Eledrisi, Noor Nabeel Suleiman, Obada Salameh, Mohammad Khair Hamad, Omar Rabadi, Ahmed Moham... Publish Year: 2019
Author: Mohsen Eledrisi, Noor Nabeel Suleiman, Obada Salameh, Mohammad Khair Hamad, Omar Rabadi, Ahmed Moham...
Publish Year: 2019
DA: 21 PA: 32 MOZ Rank: 40
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Benefits of twice-daily injection with insulin glargine: a …
https://pubmed.ncbi.nlm.nih.gov/20345066/
We propose that patients with hypoglycemia despite titration of once daily Glargine should be considered for a twice-daily regimen. Despite a slight increase in cost and inconvenience for the patient, the increases frequency of administration may result in a greater success in achieving glycemic targets. Author: Dima Youssef, Adel El Abbassi, Garren Woodby, Alan N Peiris Publish Year: 2010
Author: Dima Youssef, Adel El Abbassi, Garren Woodby, Alan N Peiris
Publish Year: 2010
DA: 45 PA: 16 MOZ Rank: 12
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Insulin Glargine in Critically ill Patients: Once/Day versus …
https://pubmed.ncbi.nlm.nih.gov/31995840/
Additionally, the twice/day group did not experience an increased incidence of hypoglycemia (twice/day 23% vs once/day 34%, p=0.57) or hypoglycemia without having anything by mouth (twice/day 0% vs once/day 9%, p=0.27). Conclusions: This is the first study demonstrating that twice/day insulin glargine reduced the rate of predose hyperglycemia without increasing the … Author: Marlena A. Fox, Melanie C. Perry, Xi Liu‐DeRyke Publish Year: 2020
Author: Marlena A. Fox, Melanie C. Perry, Xi Liu‐DeRyke
Publish Year: 2020
DA: 11 PA: 19 MOZ Rank: 27
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Dosing Lantus® (insulin glargine injection) 100 Units/mL
https://www.lantus.com/hcp/dosing-injection/insulin-dose-and-dosing-calculator
The recommended starting dose of Lantus ® in patients with type 2 diabetes who are not currently treated with insulin is 0.2 Units/kg or up to 10 Units once daily, adjusted to patient’s appropriate FPG target. One may need to adjust the amount and timing of short- or rapid-acting insulins and dosages of any oral anti-diabetic drugs
DA: 22 PA: 83 MOZ Rank: 11
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Is Twice-Daily Insulin Glargine Superior to Once-Daily …
https://professional.diabetes.org/abstract/twice-daily-insulin-glargine-superior-once-daily-administration
Patients received full-dose insulin glargine once daily at 0800 and half-dose insulin glargine twice-daily at 0800 and 2000 on successive weeks in random order prior to the two admits. Insulin glargine was held on the day prior to admission to prevent carryover of insulin into the study period, and overnight glucose was stabilized with IV insulin on the evening prior to study.
DA: 25 PA: 54 MOZ Rank: 91
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Dosing | BASAGLAR® (insulin glargine) injection
https://www.basaglar.com/hcp/dosing
From Toujeo® (insulin glargine injection) 300 units/mL The recommended initial BASAGLAR dosage is 80% of the Toujeo dose that is being discontinued This dosage reduction will lower the likelihood of hypoglycemia From NPH (neutral protamine Hagedorn) insulin (twice-daily)
DA: 32 PA: 33 MOZ Rank: 91
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Lantus Dosing Twice A Day | DiabetesTalk.Net
https://diabetestalk.net/diabetes/lantus-dosing-twice-a-day
Jan 06, 2018 · This slow dissolution results in a slower onset and a lack of a peak effect compared to other insulins, as shown below: Efficacy of Daily versus Twice-Daily Lantus Administration Although insulin glargine should last a full 24 hours, there is some evidence that its duration of action may be reduced to 20-23 hours, particularly following injection due to its …
DA: 25 PA: 43 MOZ Rank: 48
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Splitting Lantus Into 2 Doses - DiabetesTalk.Net
https://diabetestalk.net/diabetes/splitting-lantus-into-2-doses
Jan 06, 2018 · although insulin glargine is us food and drug administration-approved for once-daily dosing, the actual duration of action ranges from 10.8 to more than 24 hours in some patients. [ 1 , 2 ] this fairly wide range suggests that a second dose may be necessary to achieve optimal glycemic control, although this is considered off-label use. [ 3 , 4 ] …
DA: 99 PA: 5 MOZ Rank: 81
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Guidelines for adjusting twice-daily insulin therapy
https://www.therotherhamft.nhs.uk/Patient_Information/Patient_Information_Leaflets/Guidelines_for_adjusting_twice-daily_insulin_therapy_(Low_vision_version)_-_Diabetes_Service/
Guidelines for adjusting twice-daily insulin therapy Remember the ‘3 day’ rule if your blood sugar reading is above target The guidelines on the next page explain what you need to do if your blood sugar levels are above the target range for three days in a row. Only increase insulin 2 units at a time. Only adjust one insulin dose at a time.
DA: 22 PA: 64 MOZ Rank: 66
