Keyword Analysis & Research: insulin degludec vs glargine dosing
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Efficacy and Safety of Degludec versus Glargine in Type 2 …
https://www.nejm.org/doi/full/10.1056/NEJMoa1615692
WEBAug 24, 2017 · For basal insulin, the estimated dose of degludec was 2 units higher than the dose of glargine (estimated treatment ratio, 1.04; 95% CI, 1.00 to 1.08; P=0.04) at 24 months (Fig. S11 in the ...
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Interchange Recommendations - American Diabetes …
https://diabetes.org/sites/default/files/2019-08/switching-between-insulin.pdf
WEBToujeo® (glargine U-300) Tresiba® (degludec U-100 & U-200) Interchange Recommendations: Basal insulin analogs may be interchanged with NPH with a 20% reduction in dose and divided based on predicted meal frequency • if eating 2 meals per day- Split the new dose into ½ NPH with first meal of the day and ½ NPH with second …
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Type 2 Diabetes Mellitus: Outpatient Insulin Management | AAFP
https://www.aafp.org/pubs/afp/issues/2018/0101/p29.html
WEBJan 1, 2018 · The efficacy and safety of insulin degludec given in variable once-daily dosing intervals compared with insulin glargine and insulin degludec dosed at the same time daily: a...
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Tresiba vs. Lantus: What’s the Difference? - Verywell Health
https://www.verywellhealth.com/tresiba-vs-lantus-what-s-the-difference-8421007
WEBJan 24, 2024 · Tresiba (insulin degludec) and Lantus (insulin glargine) are Food and Drug Administration (FDA)-approved synthetic insulins for glycemic control (blood sugar levels) in people with type 1 or type 2 diabetes. This article will compare and contrast these insulin products.
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Efficacy and Safety of Insulin Degludec versus Insulin Glargine: A
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867587/
WEBMar 12, 2018 · Compared with IGlar, IDeg is associated with equivalent glycemic control and a statistically significantly lower rate of nocturnal hypoglycemia in patients with T1DM and T2DM. In T2DM patients, IDeg also provides better results in terms of overall hypoglycemia. Go to: 1. Introduction.
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Efficacy and Safety of Degludec versus Glargine in Type 2 …
https://www.nejm.org/doi/pdf/10.1056/NEJMoa1615692
WEBJun 12, 2017 · degludec (3818 patients) or insulin glargine U100 (3819 patients) once daily between dinner and bedtime in a double-blind, treat-to-target, event-driven cardiovascular out- comes trial.
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Practical guidance on the initiation, titration, and switching of …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231382/
WEBJun 24, 2021 · A simple rule is to gradually increase the initial dose by 1 unit per day (NPH, insulin detemir, and glargine 100 units/mL) or 2–4 units once or twice per week (NPH, insulin detemir, glargine 100 and 300 units/mL, and degludec) until FPG levels remain consistently within the target range.
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Efficacy and Safety of Degludec Compared to Glargine 300 …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501520/
WEBApr 11, 2019 · Previously, it has been shown that glargine U300 has a more stable pharmacodynamic profile compared to glargine U100. 5 In comparison to both concentrations of glargine, degludec has lower day-to-day variability in glucose-lowering effects. 3, 9 Contrasting results were observed in two studies comparing degludec and …
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Insulin Degludec Versus Insulin Glargine in Insulin-Naive Patients …
https://diabetesjournals.org/care/article/35/12/2464/38542/Insulin-Degludec-Versus-Insulin-Glargine-in
WEBNov 14, 2012 · RESULTS. In all, 1,030 participants (mean age 59 years; baseline A1C 8.2%) were randomized (degludec 773, glargine 257). Reduction in A1C with degludec was similar (noninferior) to that with glargine (1.06 vs. 1.19%), with an estimated treatment difference of degludec to glargine of 0.09% (95% CI −0.04 to 0.22).
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Tresiba vs. Lantus: What to Know About Each - Healthline
https://www.healthline.com/health/drugs/tresiba-vs-lantus
WEBJan 24, 2021 · Ingredients. Uses. Dosage, forms, and administration. Switching drugs. Side effects. Costs. Effectiveness. Warnings. What to ask your doctor. Q&A. Introduction. If you have type 1 or type 2...
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