Keyword Analysis & Research: eukaryotic dna replication definition biology


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How does DNA become accessible for replication in eukaryotes?

Eukaryotic DNA is bound to proteins known as histones to form structures called nucleosomes. During initiation, the DNA is made accessible to the proteins and enzymes involved in the replication process. There are specific chromosomal locations called origins of replication where replication begins.

What are the differences between eukaryotic and prokaryotic DNA replication?

The rate of replication is approximately 100 nucleotides per second, much slower than prokaryotic replication. The number of DNA polymerases in eukaryotes is much more than prokaryotes: 14 are known, of which five are known to have major roles during replication and have been well studied.

What enzymes are involved in eukaryotic DNA replication?

The overall process is the same, although differently named enzymes fulfill the same function. For example, DNA pol III is used for the majority of replication in prokaryotes, while in eukaryotes the leading strand is continuously synthesized by the enzyme pol δ, the lagging strand is synthesized by pol ε.

What proteins are involved in eukaryotic DNA replication?

They are known as pol α, pol β, pol γ, pol δ, and pol ε. The essential steps of replication are the same as in prokaryotes. Before replication can start, the DNA has to be made available as template. Eukaryotic DNA is bound to basic proteins known as histones to form structures called nucleosomes.

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