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DNA replication - Wikipedia
The replication fork is a structure that forms within the long helical DNA during DNA replication. It is created by helicases, which break the hydrogen bonds …
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DNA polymerase - Wikipedia
A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA.These enzymes are essential for DNA replication and usually work in groups to create two identical DNA duplexes from a single original DNA duplex. During this process, DNA polymerase "reads" the existing …
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Origin of replication - Wikipedia
The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated. Propagation of the genetic material between generations requires timely and accurate duplication of DNA by semiconservative replication prior to cell division to ensure each daughter cell receives the full complement of chromosomes.
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DNA Replication- definition, enzymes, steps, mechanism, …
Aug 02, 2020 · The replication fork is formed during DNA strand unwinding by the helicase enzyme which exposes the origin of replication. A short RNA primer is synthesized by primase and elongation done by DNA polymerase. The replication fork moves in the direction of the new strand synthesis. The new DNA strands are synthesized in two orientations, i.e 3 ...
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Stalled replication fork protection limits cGAS–STING and P-body
Jul 11, 2022 · Emam et al. report that Abro1 and FANCD2 protect stalled replication forks from degradation, thereby preventing the accumulation of cytosolic ribosomal DNA and the activation of cGAS–STING- and ...
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DNA replication - California State University, Northridge
DNA replication: ¥Copying genetic information for transmission to the next generation ¥Occurs in S phase of cell cycle ¥Process of DNA duplicating itself ¥Begins with the unwinding of the double helix to expose the bases in each strand of DNA ¥Each unpaired nucleotide will attract a complementary nucleotide from the medium
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DNA Replication - The Cell - NCBI Bookshelf
As discussed in Chapter 3, DNA replication is a semiconservative process in which each parental strand serves as a template for the synthesis of a new complementary daughter strand. The central enzyme involved is DNA polymerase, which catalyzes the joining of deoxyribonucleoside 5′-triphosphates (dNTPs) to form the growing DNA chain. However, DNA …
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What is DNA replication? – YourGenome
Jul 21, 2021 · The separation of the two single strands of DNA creates a ‘Y’ shape called a replication ‘fork’. The two separated strands will act as templates for making the new strands of DNA. One of the strands is oriented in the 3’ to 5’ direction (towards the replication fork), this is the leading strand.
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DNA Replication: Definition, and Significance - Embibe
Jul 20, 2022 · Elongation of DNA Replication. Following are the steps followed during the elongation of DNA replication: Activation of Deoxyribonucleotides: Deoxyribonucleotides occur freely inside the nucleoplasm in the form of monophosphates.So, they are first phosphorylated and changed to active forms of triphosphates with the help of the enzyme phosphorylase …
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DNA replication - Online Biology Notes
Jun 14, 2017 · DNA replication. DNA replication is fundamental process occurring in all living organism to copy their DNA. The process is called replication in sense that each strand of ds DNA serve as template for reproduction of complementary strand. ... In elongation steps, helicasein front of primaseand pol III, unwind the DNA at the replication fork and ...
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