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CXCL8 Gene - GeneCards | IL8 Protein | IL8 Antibody
https://www.genecards.org/cgi-bin/carddisp.pl?gene=CXCL8
WEBJan 3, 2024 · CXCL8 (C-X-C Motif Chemokine Ligand 8) is a Protein Coding gene. Diseases associated with CXCL8 include Adult Respiratory Distress Syndrome and Melanoma. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway.
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Interleukin 8 - Wikipedia
https://en.wikipedia.org/wiki/Interleukin_8
WEBInterleukin 8 (IL-8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. Endothelial cells store IL-8 in their storage vesicles, the Weibel-Palade bodies .
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白细胞介素8/IL-8的信号通路 - 知乎 - 知乎专栏
https://zhuanlan.zhihu.com/p/353791713
WEBMar 1, 2021 · il-8,又称cxcl8,是一种cxc型趋化因子,最初被鉴定为白细胞趋化剂。 IL-8由多种细胞分泌,包括白细胞、成纤维细胞、内皮细胞和恶性tumor细胞。 IL-8基因编码99个氨基酸的前体蛋白,经过加工,在非免疫细胞中产生7…
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白细胞介素-8 - 维基百科,自由的百科全书
https://zh.wikipedia.org/wiki/%E7%99%BD%E7%BB%86%E8%83%9E%E4%BB%8B%E7%B4%A0-8
WEB白细胞介素-8(英語: Interleukin-8 ,简称为白介素-8或IL-8,亦称为趋化因子CXCL8)是巨噬细胞和上皮细胞等分泌的细胞因子 。白细胞介素-8结合趨化因子受体白细胞介素-8受体α(IL8RA, 又叫CXCR1)和白细胞介素-8受体β(IL8RB, 又叫CXCR2)而对嗜中性粒细胞(neutrophils)有细胞 ...
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The chemokines CXCL8 and CXCL12: molecular and functional …
https://www.nature.com/articles/s41423-023-00974-6
WEBFeb 1, 2023 · CXCL8 is the most potent human neutrophil-attracting chemokine and plays crucial roles in the response to infection and tissue injury.
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The role of CXCL family members in different diseases
https://www.nature.com/articles/s41420-023-01524-9
WEBJul 1, 2023 · CXCL8, secreted by macrophages and epithelial cells, is an active angiogenic factor and proinflammatory factor, taking part in the cancer development, including change of tumor microenvironment...
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The CXCL8/IL-8 chemokine family and its receptors in …
https://pubmed.ncbi.nlm.nih.gov/24678812/
WEBCXCL8 (interleukin-8) is a member of the chemokine family that acts on CXCR1 and CXCR2 receptors. CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, and CXCL7 are also ELR+ chemokine members that bind to these receptors, especially CXCR2. The majority of studies on the biology of CXCL8 and their receptors have been performed in …
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CXCL8 in Tumor Biology and Its Implications for Clinical Translation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965068/
WEBMar 15, 2022 · CXCL8 is one of the ELR + CXC chemokines (Baldwin et al., 1991). The gene encoding CXCL8 is located on 4q13-q21 (Modi et al., 1990). There are four common polymorphisms in the CXCL8 gene: rs4073(-251 A/T), rs2227532(-845T/C), rs2227307(+396 G/T) and rs2227306(+781 C/T) (Mukaida et al., 1989; Yao et al., 2019).
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白细胞介素-8_百度百科
https://baike.baidu.com/item/%E7%99%BD%E7%BB%86%E8%83%9E%E4%BB%8B%E7%B4%A0-8/2967640
WEB白细胞介素-8 (白介素-8, Interleukin-8, IL-8), 又称为趋化因子CXCL8是 巨噬细胞 和 上皮细胞 等分泌的 细胞因子 。. 白细胞介素-8结合趋化因子受体 白细胞介素-8受体 α (IL8RA, 又叫CXCR1)和白细胞介素-8受体β (IL8RB, 又叫CXCR2)而对 中性粒细胞 有细胞 趋化作用 而实 …
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CXCL8 C-X-C motif chemokine ligand 8 [ (human)] - National …
https://www.ncbi.nlm.nih.gov/gene/3576/
WEBCXCL8 is predominantly secreted by macrophages and contributes to the immunosuppressive microenvironment by inducing PD-L1(+) macrophages in gastric cancer. CXCL8 inhibitors may drive antitumour response, providing potential therapeutic effects for patients with gastric cancer.
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