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CXCL5 - Wikipedia
https://en.wikipedia.org/wiki/CXCL5
WebThe protein encoded by this gene, CXCL5 is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. [7]
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CXCL5 Gene - GeneCards | CXCL5 Protein | CXCL5 Antibody
https://www.genecards.org/cgi-bin/carddisp.pl?gene=CXCL5
WebApr 2, 2024 · GeneCards Summary for CXCL5 Gene. CXCL5 (C-X-C Motif Chemokine Ligand 5) is a Protein Coding gene. Diseases associated with CXCL5 include Pulmonary Sarcoidosis and Extrinsic Allergic Alveolitis . Among its related pathways are MIF Mediated Glucocorticoid Regulation and GPCR downstream signalling .
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CXCL5: A coachman to drive cancer progression - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376318/
WebAug 1, 2022 · Considering the important functions of CXCL5 in tumor differentiation, advanced tumor stages, local invasion, neutrophil infiltration, and metastasis, CXCL5 has been considered a potential biomarker for prognosis and a novel preventive and therapeutic target for cancer.
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The role of CXCL family members in different diseases
https://www.nature.com/articles/s41420-023-01524-9
WebJul 1, 2023 · CXCL5, known as epithelial activating neutrophil protein, plays a role in immune system and inflammation. CXCL6, also known as granulocyte chemotactic protein 2, is a chemoattractant...
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CXCL5 activates CXCR2 in nociceptive sensory neurons to drive …
https://www.nature.com/articles/s41467-024-47640-7
WebApr 16, 2024 · Here, the authors demonstrate that CXCL5 expression is increased in ankle joints of gouty arthritis model mice. CXCL5-neuronal CXCR2-TRPA1 axis contributes to gouty arthritis pain, neutrophil ...
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CXCL5 signaling is a shared pathway of neuroinflammation and …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704424/
WebJan 6, 2016 · CXCL5 is a potential biomarker for white matter injury in preterm infants. Pharmacological blockade of CXCL5 signaling that attenuates dysregulated neuroinflammation can be used a therapeutic strategy against white matter injury in the immature brain. Electronic supplementary material.
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CXCL5 promotes gastric cancer metastasis by inducing ... - Nature
https://www.nature.com/articles/s41389-020-00249-z
WebJul 6, 2020 · CXCL5 promotes gastric cancer metastasis by inducing epithelial-mesenchymal transition and activating neutrophils | Oncogenesis. Article. Open access. Published: 06 July 2020. CXCL5 promotes...
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CXCL5: A coachman to drive cancer progression - PubMed
https://pubmed.ncbi.nlm.nih.gov/35978824/
WebAug 1, 2022 · C-X-C motif chemokine ligand 5 (CXCL5) is a member of the chemokine family binding CXCR2 (C-X-C Motif Chemokine Receptor 2), a G-protein coupled receptor. Accumulated evidence has shown that dysregulated CXCL5 participates in tumor metastasis and angiogenesis in human malignant tumors.
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CXCL5/CXCR2 axis in tumor microenvironment as potential …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163794/
WebMar 31, 2020 · CXCL5 promotes the migratory and invasive abilities of tumor cells to distant organs through blood vessels and lymphatic vessels. CXCL5 recruits more immune‐related cells, such as neutrophils, T cells and MDSCs, from the blood vessels to the tumor microenvironment.
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CXCL5 - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/neuroscience/cxcl5
WebThe most relevant CXC chemokines involved in the pathogenesis of arthritis are CXCL1 (groα), CXCL4 (platelet factor 4; PF4), CXCL5 (epithelial cell–derived neutrophil attractant 78; ENA-78), CXCL6 (granulocyte chemotactic protein 2; GCP-2), CXCL7 (connective tissue–activating protein III; CTAP-III), CXCL8 (IL-8), CXCL9 (Mig), CXCL10 (IFN ...
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