Keyword Analysis & Research: cxcl1
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CXCL1 - Wikipedia
https://en.wikipedia.org/wiki/CXCL1
WebThe chemokine (C-X-C motif) ligand 1 (CXCL1) is a small peptide belonging to the CXC chemokine family that acts as a chemoattractant for several immune cells, especially neutrophils or other non-hematopoietic cells to the site of injury or infection and plays an important role in regulation of immune and inflammatory responses. It was ...
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The role of CXCL family members in different diseases
https://www.nature.com/articles/s41420-023-01524-9
WebJul 1, 2023 · CXCL1, known as growth related oncogene, can be expressed in many immune cells and neurons. The main function of CXCL1 is recruitment of immunocytes, especially neutrophils [ 8 ].
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CXCL1 C-X-C motif chemokine ligand 1 [ (human)] - National …
https://www.ncbi.nlm.nih.gov/gene/2919
WebApr 7, 2024 · The positive expression of CXCL1 is correlated with poor survival of gastric cancer patients and CXCL1 is an independent prognostic factor for gastric cancer. These results demonstrate that tumor-derived CXCL1 contributes to TANs infiltration in lung cancer which promotes tumor growth.
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CXCL1: Gene, Promoter, Regulation of Expression, mRNA …
https://pubmed.ncbi.nlm.nih.gov/35054978/
WebJan 12, 2022 · CXCL1 is one of the most important chemokines, part of a group of chemotactic cytokines involved in the development of many inflammatory diseases. It activates CXCR2 and, at high levels, CXCR1. The expression of CXCL1 is elevated in inflammatory reactions and also has important functions in physiology, including the …
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CXCL1 Gene - GeneCards | GROA Protein | GROA Antibody
https://www.genecards.org/cgi-bin/carddisp.pl?gene=CXCL1
WebApr 2, 2024 · GeneCards Summary for CXCL1 Gene. CXCL1 (C-X-C Motif Chemokine Ligand 1) is a Protein Coding gene. Diseases associated with CXCL1 include Tonsillitis and Bacterial Meningitis . Among its related pathways are MIF Mediated Glucocorticoid Regulation and GPCR downstream signalling .
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CXCL1 derived from tumor-associated macrophages promotes
https://www.nature.com/articles/s41419-018-0876-3
WebAug 29, 2018 · Here in, cytokine array validated that C-X-C motif chemokine ligand 1 (CXCL1) is the most abundant chemokine secreted by TAMs, and CXCL1 can promote breast cancer migration and...
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Blocking the CXCL1-CXCR2 axis enhances the effects of ... - Nature
https://www.nature.com/articles/s41420-023-01424-y
WebApr 10, 2023 · Cell Death Discovery - Blocking the CXCL1-CXCR2 axis enhances the effects of doxorubicin in HCC by remodelling the tumour microenvironment via the NF-κB/IL-1β/CXCL1 signalling pathway
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The Importance of CXCL1 in Physiology and Noncancerous …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024980/
WebApr 11, 2022 · Due to the vast amount of available information, we focus on the role CXCL1 plays in the physiology of bones, bone marrow, muscle and the nervous system. For this reason, we describe its effects on hematopoietic stem cells, myoblasts, oligodendrocyte progenitors and osteoclast precursors.
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Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296306/
WebLevels of Cxcl1 (A and E), Cxcl2 (C and G), Cxcl1 dimer (B and F), and Cxcl2 dimer (D and H) in the peritoneum (top row, A–D) and blood (bottom row, E–H) at 3 and 15 h postinjection determined using ELISA. Chemokine levels are expressed in absorbance (O.D.) units from …
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CXCL1 - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/cxcl1
WebIn summary, CXCL1/CXCR2 signaling in cancer cells modulates tumor progression by enhancing cell growth, motility, and invasion. CXCL1 also signals to CXCR2 + stromal cells to regulate cancer progression.
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