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Direct Oral Anticoagulant Use: A Practical Guide to Common …
https://www.ahajournals.org/doi/10.1161/JAHA.120.017559
WEBDirect oral anticoagulants (DOACs)—dabigatran (Pradaxa), rivaroxaban (Xarelto), apixaban (Eliquis), edoxaban (Savaysa), and betrixaban (Bevyxxa) are anticoagulation pharmacotherapy used for the prevention of thrombosis in several cardiovascular contexts. 1 DOACs are categorized into 2 main classes: oral direct factor Xa inhibitors (ie ...
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Direct oral anticoagulants (DOACs) and parenteral direct ... - UpToDate
https://www.uptodate.com/contents/direct-oral-anticoagulants-doacs-and-parenteral-direct-acting-anticoagulants-dosing-and-adverse-effects
WEBMar 1, 2024 · Apixaban - Overview (apixaban) - Dosing, monitoring, risks (apixaban) Edoxaban - Overview (edoxaban) - Dosing, monitoring, risks (edoxaban) Betrixaban; TRANSITIONING BETWEEN ANTICOAGULANTS. From a DOAC to warfarin or another DOAC; From a VKA to a DOAC or argatroban; Between DOACs and heparins; …
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Laboratory Monitoring of Direct Oral Anticoagulants (DOACs)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143174/
WEBApr 21, 2021 · The introduction of direct oral anticoagulants (DOACs), such as dabigatran, rivaroxaban, apixaban, edoxaban, and betrixaban, provides safe and effective alternative to previous anticoagulant therapies. DOACs directly, selectively, and reversibly inhibit factors IIa or Xa.
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Direct Oral Anticoagulants and Coronary Artery Disease
https://www.ahajournals.org/doi/10.1161/ATVBAHA.121.317171
WEBMar 17, 2022 · The drug has a renal clearance of 33%. 14 Rivaroxaban has the greatest bioavailability of the DOACs at approximately 80%. Apixaban is also a direct factor Xa inhibitor that is dosed twice daily and has a time-to-peak effect of 1-2 hours. Apixaban is the least renally cleared of the DOACs at 27%.
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Pre-Procedural DOAC Guidance: When or If to Hold for …
https://www.acc.org/latest-in-cardiology/articles/2017/12/18/09/43/pre-procedural-doac-guidance
WEBDec 18, 2017 · The pharmacological properties of the four commercially available DOACs indicated for NVAF (dabigatran, rivaroxaban, apixaban, and edoxaban) are outlined in Table 1. 2-5 Although risks of major bleeding events with EP/catheterization procedures are relatively low, management of bleeding associated with DOACs can be challenging due …
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Oral Apixaban for the Treatment of Acute Venous …
https://www.nejm.org/doi/full/10.1056/NEJMoa1302507
WEBFeb 22, 2024 · With these characteristics, apixaban may simplify the treatment of venous thromboembolism by eliminating the need for initial parenteral anticoagulant therapy and laboratory monitoring, a concept...
DA: 78 PA: 55 MOZ Rank: 12
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Direct Oral Anticoagulants: A Quick Guide - PMC - National …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206466/
WEBNov 29, 2016 · Apixaban was associated with a decreased rate of major bleeding compared with other DOACs in patients with a creatinine clearance of <50 ml/min. A retrospective matched-cohort study assessed the safety and efficacy of apixaban versus warfarin in patients with a creatinine clearance of <25 ml/min, serum creatinine …
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Apixaban for the Treatment of Venous Thromboembolism …
https://www.nejm.org/doi/full/10.1056/NEJMoa1915103
WEBFeb 29, 2024 · Oral apixaban was noninferior to subcutaneous dalteparin for the treatment of cancer-associated venous thromboembolism without an increased risk of major bleeding.
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Direct Oral Anticoagulant Use: A Practical Guide to Common …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670541/
WEBJul 7, 2020 · Go to: Abstract. Direct oral anticoagulants ( DOAC s) have quickly become attractive alternatives to the long‐standing standard of care in anticoagulation, vitamin K antagonist. DOAC s are indicated for prevention and treatment of …
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What are Direct-Acting Oral Anticoagulants (DOACs)?
https://www.heart.org/-/media/files/health-topics/answers-by-heart/what-are-doacs.pdf?la=en
WEBSome DOAC medications include: • Apixaban (Eliquis) • Betrixaban (Bevyxxa) • Dabigatran (Pradaxa) You may know about anticoagulants as “blood . thinners” used to treat certain blood vessel, heart . and lung conditions, including atrial fibrillation (AFib), peripheral artery disease and venous thromboembolism.
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