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ACVR1 - Wikipedia
https://en.wikipedia.org/wiki/ACVR1
Web ResultActivin A receptor, type I (ACVR1) is a protein which in humans is encoded by the ACVR1 gene; also known as ALK-2 (activin receptor-like kinase-2). ACVR1 has been linked to the 2q23-24 region of the genome.
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ACVR1 Function in Health and Disease - PMC - National Center …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912516/
Web ResultOct 31, 2019 · Activin A receptor type I (ACVR1) encodes for a bone morphogenetic protein type I receptor of the TGFβ receptor superfamily. It is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation.
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ACVR1 Gene - GeneCards | ACVR1 Protein | ACVR1 Antibody
https://www.genecards.org/cgi-bin/carddisp.pl?gene=ACVR1
Web ResultJan 3, 2024 · ACVR1 (Activin A Receptor Type 1) is a Protein Coding gene. Diseases associated with ACVR1 include Fibrodysplasia Ossificans Progressiva and Epicanthus. Among its related pathways are Akt Signaling and NF-kappaB Pathway. Gene Ontology (GO) annotations related to this gene include protein …
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ACVR1 gene: MedlinePlus Genetics
https://medlineplus.gov/genetics/gene/acvr1/
Web ResultThe ACVR1 gene provides instructions for making the activin receptor type-1 (ACVR1) protein, which is a member of a protein family called bone morphogenetic protein (BMP) type I receptors. Learn about this gene and related health conditions.
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ACVR1 Function in Health and Disease - PubMed
https://pubmed.ncbi.nlm.nih.gov/31683698/
Web ResultOct 31, 2019 · Abstract. Activin A receptor type I (ACVR1) encodes for a bone morphogenetic protein type I receptor of the TGFβ receptor superfamily. It is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation.
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ACVR1: A Novel Therapeutic Target to Treat Anemia in …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10778144/
Web ResultActivin receptor type I (ACVR1) is a transmembrane kinase receptor belonging to bone morphogenic protein receptors (BMPs). ACVR1 plays an important role in hematopoiesis and anemia via the BMP6/ACVR1/SMAD pathway, which regulates expression of hepcidin, the master regulator of iron homeostasis.
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Cells | Free Full-Text | ACVR1 Function in Health and Disease
https://www.mdpi.com/2073-4409/8/11/1366
Web ResultOct 31, 2019 · Abstract. Activin A receptor type I (ACVR1) encodes for a bone morphogenetic protein type I receptor of the TGFβ receptor superfamily. It is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation.
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TP-0184 inhibits FLT3/ACVR1 to overcome FLT3 inhibitor …
https://www.nature.com/articles/s41375-023-02086-6
Web ResultNov 25, 2023 · These findings suggest that ACVR1 is a novel biomarker and plays a role in AML resistance to FLT3 inhibitors and that FLT3/ ACVR1 dual inhibitor TP-0184 is a novel potential therapeutic tool...
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Multi-omics therapeutic perspective on ACVR1 gene: from genetic
https://pubmed.ncbi.nlm.nih.gov/36003055/
Web ResultApr 13, 2023 · Activin A receptor type I (ACVR1), a transmembrane serine/threonine kinase, belongs to the transforming growth factor-β superfamily, which signals via phosphorylating the downstream effectors and SMAD transcription factors. Its central role in several biological processes and intracellular signaling …
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ACVR1 gene information - The Human Protein Atlas
https://www.proteinatlas.org/ENSG00000115170-ACVR1/summary/gene
Web ResultACVR1 gene information - The Human Protein Atlas. SUMMARY. TISSUE. SINGLE CELL. TISSUE CELL. PATHOLOGY. DISEASE. IMMUNE. BLOOD. SUBCELL. CELL LINE. INTERACTION. PROTEIN SUMMARY SECTION OVERVIEW GENE INFORMATION RNA DATA ANTIBODY DATA. Contact. The Project. The Human …
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