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Adrenoleukodystrophy - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/adrenoleukodystrophy/symptoms-causes/syc-20369157
WEBFeb 7, 2020 · Adrenoleukodystrophy (uh-dree-noh-loo-koh-DIS-truh-fee) is a type of hereditary (genetic) condition that damages the membrane (myelin sheath) that insulates nerve cells in your brain. In adrenoleukodystrophy (ALD), your body can't break down very long-chain fatty acids (VLCFAs), causing saturated VLCFA s to build up in your …
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Adrenoleukodystrophy (ALD) | Johns Hopkins Medicine
https://www.hopkinsmedicine.org/health/conditions-and-diseases/adrenoleukodystrophy
WEBAdrenoleukodystrophy (ALD) is a genetic condition that damages the membrane (myelin sheath) that covers nerve cells in the brain and spinal cord. Myelin acts as insulation around the nerve fibers. When this insolating layer is damaged, nerve signals from the brain cannot communicate across the body properly, causing impaired bodily functions or ...
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Adrenoleukodystrophy | National Institute of Neurological …
https://www.ninds.nih.gov/health-information/disorders/adrenoleukodystrophy
WEBNov 28, 2023 · Adrenoleukodystrophy or ALD (also known as X-linked adrenoleukodystrophy or X-ALD) is one of a group of neurological disorders known as the leukodystrophies, which result from abnormalities in myelin—the white matter that protects nerve fibers in the brain and spinal cord.
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Adrenoleukodystrophy - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK562328/
WEBNov 8, 2020 · Adrenoleukodystrophy is a peroxisomal disorder resulting from abnormal metabolism of the very-long-chain fatty acids (VLCFA). It is classified into different subtypes based on the mode of inheritance, clinical presentation, age of onset, and organs involved.
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Adrenoleukodystrophy - Wikipedia
https://en.wikipedia.org/wiki/Adrenoleukodystrophy
WEBAdrenoleukodystrophy (ALD) is a disease linked to the X chromosome. It is a result of fatty acid buildup caused by failure of peroxisomal fatty acid beta oxidation which results in the accumulation of very long chain fatty acids in tissues throughout the body.
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Adrenoleukodystrophy (ALD): Causes, Types, Symptoms, Prognosis - WebMD
https://www.webmd.com/brain/what-is-adrenoleukodystrophy
WEBFeb 4, 2022 · What Is It? ALD causes severe damage to your nervous system. It does this by breaking apart the fatty covering (called myelin) that protects nerves in your brain and spinal cord. This makes it...
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X-linked adrenoleukodystrophy: MedlinePlus Genetics
https://medlineplus.gov/genetics/condition/x-linked-adrenoleukodystrophy/
WEBX-linked adrenoleukodystrophy is a genetic disorder that mainly affects the nervous system and the adrenal glands, which are located on top of each kidney. In this disorder, the fatty covering ( myelin) that insulates nerves in the brain and spinal cord tends to deteriorate (a condition called demyelination).
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Adrenoleukodystrophy (ALD) | Boston Children's Hospital
https://www.childrenshospital.org/conditions/adrenoleukodystrophy-ald
WEBAdrenoleukodystrophy (ALD) is a rare genetic condition that affects males and females differently. In childhood, boys are primarily affected. Girls are not typically affected, though they may develop symptoms as adults. ALD is caused by mutations in the ABCD1 gene that prevent the body from breaking down very-long-chain fatty acids (VLCFAs). As ...
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Adrenoleukodystrophy - Diagnosis and treatment - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/adrenoleukodystrophy/diagnosis-treatment/drc-20369160
WEBFeb 7, 2020 · Find out about diagnosis and treatment of adrenoleukodystrophy — a hereditary disorder that affects the brain, nervous system and adrenal gland.
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ALD: Adrenoleukodystrophy, Disease, X-Linked - Cleveland Clinic
https://my.clevelandclinic.org/health/diseases/6030-adrenoleukodystrophy-ald
WEBMay 17, 2021 · Adrenoleukodystrophy, ALD, is a genetic disorder connected to the X chromosome. It affects the nervous system and adrenal glands. Symptoms of ALD often include behavioral and cognitive changes. ALD affects males more than females. Treatment focuses on stopping or slowing the disease’s progression and improving symptoms.
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